Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm).
体外研究
After incubation with Ac-DEVD-AFC for 1 hour, significant increase of caspase-3 activity is observed at 4 hour compare with control. There are no significant increases of caspase-3 activity in Photofrin and LPLI group. The cleavage of Ac-DEVD-AFC in response to caspase-3 activation is remarkably inhibited by shRNA-BimL transfection.
分子式
C30H34N5O13F3
分子量
729.61
CAS号
201608-14-2
运输条件
Room temperature in continental US; may vary elsewhere.