Avexitide (Exendin (9-39)) 是特异竞争性的 glucagon-like peptide-1 (GLP-1) 受体拮抗剂。
| 生物活性 |
Avexitide (Exendin (9-39)) is a specific and competitive GLP-1 receptor antagonist. |
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| 体外研究 |
GLP-1 plays a role in the control of fasting glucose. Avexitide (Exendin (9-39)), a truncated form of the GLP-1 agonist exendin-4, is a specific GLP-1 receptor antagonist. |
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| 体内研究 |
Continuous subcutaneous infusion of Avexitide (Exendin (9-39)) significantly raises fasting blood glucose levels in SUR-1 mice without affecting glucose tolerance.
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| 分子式 |
C149H234N40O47S
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| 分子量 |
3369.76
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| CAS号 |
133514-43-9
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
H2O : 50 mg/mL (14.84 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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| 临床试验 |
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| 科研文献 |
纯度： 98%
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