| 生物活性 |
Biotin-cholesterol is a biotinylated form of Cholesterol. Biotin-cholesterol is a liver-targeting ligand (linking cholesterol and biotin via a Gly-Lys dipeptide linker), as well as an enhancer of the component activity of streptavidin-mediated siRNA nanocomplexes. Biotin-cholesterol promotes receptor-mediated endocytosis of the relevant siRNA nanocomplexes, protects siRNA from serum degradation, enables efficient siRNA delivery, and drives target gene silencing. Biotin-cholesterol shows no cytotoxicity in hepatic stellate cells. Biotin-cholesterol can be used in the research of alcoholic liver fibrosis.
|
|---|---|
| 分子式 |
C37H60N2O3S
|
| 分子量 |
612.95
|
| CAS号 |
2454045-15-7
|
| 中文名称 |
生物素胆固醇
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
4°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
纯度： 97%
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