244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels.
分子式
C60H111N3O6
分子量
970.54
CAS号
2956402-64-3
中文名称
244cis
运输条件
Room temperature in continental US; may vary elsewhere.