| 生物活性 |
2-Oleoylglycerol-d5 (2-OG-d5) is the deuterium labeled 2-Oleoylglycerol . 2-Oleoylglycerol (2-OG) is a lipid found in the diet. It is a GPR119 agonist, with an EC50 value of 2.5 μM in activating hGPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol enhances the inflammatory response of macrophages and promotes fibrosis by activating the GPR119/TAK1/NF-κB/TGF-β1 signaling pathway. It also stimulates glucagon-like peptide 1 (GLP-1) secretion in vivo. 2-Oleoylglycerol is expected to be used in the research of non-alcoholic steatohepatitis (NASH) .
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| 分子式 |
C21H35D5O4
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| 分子量 |
361.57
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| CAS号 |
946524-37-4
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| 中文名称 |
2-油酰基甘油-d5
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
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