PF-5212374 (Synonyms:(TRU-015))
目录号 : KM35666 CAS No. : 1169717-01-4 纯度 : 97%
PF-5212374 (TRU-015) 是 CHO 表达的人源抗体,靶向 CD20/MS4A1。PF-5212374 具有强效的直接信号传导和抗体依赖的细胞毒性。PF-5212374 补体依赖的细胞毒性比 Rituximab 低。PF-5212374 具有抗肿瘤的活性。PF-5212374 可用于淋巴瘤等肿瘤和炎症性疾病的研究。
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生物活性
PF-5212374 (TRU-015) is a humanized antibody expressed in CHO, targeting CD20/MS4A1. PF-5212374 exhibits potent direct signaling and antibody-dependent cellular cytotoxicity, with complement-mediated cytotoxicity lower than that of Rituximab . PF-5212374 has antitumor activity and can be used in the research of tumors such as lymphoma and inflammatory diseases.
CAS号
1169717-01-4
运输条件
Shipping with dry ice.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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