1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) is an abundant lysophosphatidic acid (LPA) species with high biological activity due to its strong affinity for the LPA receptors. 1-Oleoyl lysophosphatidic acid is commonly used in most laboratories as a reagent for LPA receptor activation. 1-Oleoyl lysophosphatidic acid increases SRE-driven β-galactosidase activity.
体内研究
1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) (0.4-2 μg; i.c.v.; 9-week-old male Wistar rats) induces anxiety-like responses in the elevated plus maze (EPM) under novelty conditions.
Animal Model:
9-week-old male Wistar rats
Dosage:
0.4-2 μg
Administration:
I.c.v.
Result:
Reduced open arm exploration under novelty conditions and had no effect under habituated conditions in the EPM.
分子式
C21H41O7P
分子量
436.52
CAS号
65528-98-5
运输条件
Room temperature in continental US; may vary elsewhere.