5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitamin D3. Vitamin D3 is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
体外研究
Normal human keratinocytes in the cultured human keratinocytes by determining their influence on H-thymidine incorporation into DNA. 5,6-trans-vitamin D3 only induces significant inhibition at 10 M. The dissociation constants of vitamin D receptor (VDR) for 5,6-trans-vitamin D3 is 560 nM.
分子式
C27H44O
分子量
384.64
CAS号
22350-41-0
中文名称
5,6-反式维生素D3;5,6-反式胆钙化醇;5,6-反式胆骨化醇
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
-20°C, protect from light, stored under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶解性数据
In Vitro:
Ethyl Acetate : ≥ 50 mg/mL (129.99 mM)
*"≥" means soluble, but saturation unknown.
配制储备液
浓度溶剂体积质量
1 mg
5 mg
10 mg
1 mM
2.5998 mL
12.9992 mL
25.9983 mL
5 mM
0.5200 mL
2.5998 mL
5.1997 mL
10 mM
0.2600 mL
1.2999 mL
2.5998 mL
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。