Darunavir-d9 - CAS:1133378-37-6

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Darunavir-d9 (Synonyms:TMC114-d9; UIC-94017-d9)

目录号 : KM10391 CAS No. : 1133378-37-6

Data Sheet 产品使用指南

Darunavir-d9 (TMC114-d9) 是 Darunavir 的氘代物。Darunavir (TMC114) 是一个口服有效的、二代 HIV 蛋白酶抑制剂，对突变型病毒和野生型病毒有类似的抗病毒活性。Darunavir (TMC114) 对实验室 HIV-1 毒株和临床分离株 (IC₅₀ = 0.003；IC₉₀ = 0.009 μM) 有效。细胞毒性小。

规格	价格	是否有货	数量
1mg	询价	In-stock
10mg	询价	In-stock

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生物活性	Darunavir-d9 (TMC114-d9) is the deuterium labeled Darunavir. Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC₅₀ = 0.003 μM; IC₉₀ = 0.009 μM) with minimal cytotoxicity.
体外研究	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
分子式	C₂₇H₃₇N₃O₇S
分子量	556.72
CAS号	1133378-37-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.