ALV1
目录号 : KM24365
CAS No. : 2438124-79-7
纯度 : 95%
ALV1 is a potent Ikaros and Helios degrader. ALV1 potently reduces the protein abundance of IKZF1-4, CK1α (casein kinase 1α, CSNK1A1) and ribosomal protein RPL4. ALV1 shows similar degradation activity towards IKZF1/2/3. ALV1 induced Helios/CRBN dimerization. ALV1 promoted IL-2 secretion to a great extent.
Other Forms of Rapamycin:
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| 生物活性 |
ALV1 is a potent Ikaros and Helios degrader. ALV1 potently reduces the protein abundance of IKZF1-4, CK1α (casein kinase 1α, CSNK1A1) and ribosomal protein RPL4. ALV1 shows similar degradation activity towards IKZF1/2/3. ALV1 induced Helios/CRBN dimerization. ALV1 promoted IL-2 secretion to a great extent.
|
| 分子式 |
C25H23ClN4O5
|
| 分子量 |
494.93
|
| CAS号 |
2438124-79-7
|
| 中文名称 |
ALV1
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|