ML241 (Synonyms:2-(2,3-二氢-4H-1,4-苯并恶嗪-4-基)-5,6,7,8-四氢-N-苄基-4-喹唑啉胺)
目录号 : KF1041 CAS No. : 1346528-06-0 纯度 : 98%
ML241 (1346528-06-0) is a potent and selective p97 AAA ATPase inhibitor, IC50=100 nM. Inhibits degradation of a p97-dependent but not p97-independent proteasome substrate in a dual-reporter cell line. It impairs the endoplasmic reticulum-associated degradation (ERAD) pathway. ML241 and related inhibitors (DBeQ for example) have differential responses to p97 mutants as well as the presence of cofactors suggesting the possibility of context-dependent p97 inhibitors.
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5mg
In-stock
25mg
In-stock

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分子式
C23H24N4O
分子量
372.46
CAS号
1346528-06-0
中文名称
2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amine
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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