ML241
(Synonyms:2-(2,3-二氢-4H-1,4-苯并恶嗪-4-基)-5,6,7,8-四氢-N-苄基-4-喹唑啉胺)
目录号 : KF1041
CAS No. : 1346528-06-0
纯度 : 98%
ML241 (1346528-06-0) is a potent and selective p97 AAA ATPase inhibitor, IC50=100 nM. Inhibits degradation of a p97-dependent but not p97-independent proteasome substrate in a dual-reporter cell line. It impairs the endoplasmic reticulum-associated degradation (ERAD) pathway. ML241 and related inhibitors (DBeQ for example) have differential responses to p97 mutants as well as the presence of cofactors suggesting the possibility of context-dependent p97 inhibitors.
Other Forms of Rapamycin:
KKL Med 的所有产品和服务仅用于科学研究,不能被用于人体,兽医,我们也不向个人提供产品和服务。
KKL 顾客使用本产品发表的 0 篇科研文献
暂无科研文献
| 分子式 |
C23H24N4O
|
| 分子量 |
372.46
|
| CAS号 |
1346528-06-0
|
| 中文名称 |
2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amine
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|