NSC-33994
目录号 : KF1039
CAS No. : 82058-16-0
纯度 : 98%
NSC-33994 (82058-16-0) is a remarkably potent and selective JAK2 inhibitor (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM. Suppresses JAK2-V617F-mediated human pathological cell growth in vitro and in vivo and is concomitant with the disruption of intracellular vimentin filaments. NSC-33994 reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo.
Other Forms of Rapamycin:
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| 分子式 |
C28H42N2O2
|
| 分子量 |
436.65
|
| CAS号 |
82058-16-0
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|