NSC-47924 - CAS:6638-24-0

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NSC-47924

目录号 : KF1044 CAS No. : 6638-24-0 纯度 : 98%

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NSC-47924 (6638-24-0) is a potent inhibitor of the Leucine-rich repeat protein phosphatase (PHLPP) an enzyme which is a negative regulator of Akt and PKC (IC50=4 μM). Increases AKT signaling in cells and prevents apoptosis. Also inhibits the 67 kDa laminin receptor (LR) interaction with laminin (LM) and selectively blocks LR-293 cell adhesion to LM (IC50=19.35 μM) impairing cell migration and invasion. Affects 37/67 kDa LR cell surface localization and interaction with cellular prion protein.

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5mg		In-stock
25mg		In-stock

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分子式

C₁₈H₁₇NO₂

分子量

279.33

CAS号

6638-24-0

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： 98%

Data Sheet

SDS

产品使用指南

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