PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.
IC50&Target
CDK2
3.6 μM (Km)
CDK5
3.2 μM (Km)
分子式
C10H12ClN5O2S
分子量
301.75
CAS号
21886-12-4
运输条件
Room temperature in continental US; may vary elsewhere.