Etevritamab (Synonyms:艾替瑞妥单抗)
目录号 : KM38227 CAS No. : 2329692-74-0 纯度 : 97%
Etevritamab (AMG-596) 是一种靶向 EGFRvIII 与 CD3 的双特异性 T 细胞衔接器。Etevritamab 可同时与多形性胶质母细胞瘤上的肿瘤特异性抗原 EGFRvIII 和 T 细胞上的 CD3 结合,从而激活 T 细胞增殖并分泌细胞毒性物质,诱导结合的肿瘤细胞裂解。Etevritamab 可用于多形性胶质母细胞瘤等肿瘤的研究。
规格 价格 是否有货 数量
1mg
In-stock
5mg 询价 In-stock
10mg 询价 In-stock
50mg 询价 In-stock

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生物活性
Etevritamab (AMG-596) is a bispecific T-cell engager targeting EGFRvIII and CD3. Etevritamab can simultaneously bind to the tumor-specific antigen EGFRvIII on glioblastoma multiforme and CD3 on T cells, thereby activating T-cell proliferation and secretion of cytotoxic substances to induce lysis of the bound tumor cells. Etevritamab can be used for the research of tumors such as glioblastoma multiforme.
分子量
54.66 kDa
CAS号
2329692-74-0
中文名称
艾替瑞妥单抗
运输条件
Shipping with dry ice.
储存方式
Store at -20˚C 
暂无相关参考文献
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