| 生物活性 |
Lenalidomide-d4 (CC-5013-d4) is deuterium labeled Lenalidomide. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 分子式 |
C13H9D4N3O3
|
||||||||||||
| 分子量 |
263.29
|
||||||||||||
| CAS号 |
1130061-52-7
|
||||||||||||
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
||||||||||||
| 储存方式 |
|
关注我们
获得KKL MED 最新资讯
咨询热线：
400-881-9290
Data Sheet