WDR5-0102
(Synonyms:2-氯-N-(2-(4-甲基哌嗪-1-基)-5-硝基苯基)苯甲酰胺)
目录号 : KE9660
CAS No. : 824960-50-1
纯度 : ≥95%
WDR5-0102 is an effective and selective WDR5-MLL1 inhibitor with a Kdis value of 7 μM and Kd value of 4 μM. WDR5-0102 inhibited the activity of MLL1, but did not show the activity of human H3K4 methyltransferase SETD7 and G9a, EHMT1, SUV39H2, SETD8, PRMT3 and PRMT5.
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生物活性 |
WDR5-0102 is an effective and selective WDR5-MLL1 inhibitor with a Kdis value of 7 μM and Kd value of 4 μM. WDR5-0102 inhibited the activity of MLL1, but did not show the activity of human H3K4 methyltransferase SETD7 and G9a, EHMT1, SUV39H2, SETD8, PRMT3 and PRMT5.
|
分子式 |
C18H19ClN4O3
|
分子量 |
374.82
|
CAS号 |
824960-50-1
|
运输条件 |
Room temperature in continental US; may vary elsewhere.
|
储存方式 |
Powder |
-20°C |
3 years |
|
4°C |
2 years |
In solvent |
-80°C |
6 months |
|
-20°C |
1 month |
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