S 18986 是一种选择性的、口服活性的、脑渗透性的 AMPA-type 受体正向变构调节剂。S 18986 显示啮齿动物具有增强认知能力的特性。S 18986 激活大鼠海马去甲肾上腺素和乙酰胆碱的释放，增强大鼠在物体识别实验中的记忆。
| 生物活性 |
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests. |
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| 体内研究 |
S 18986 is robust memory-enhancing effects in middle-aged animals compared with aged ones. S 18986 shows antiamnesic properties in middle-aged rodents in spatial memory models .
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| 分子式 |
C10H12N2O2S
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| 分子量 |
224.28
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| CAS号 |
175340-20-2
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 临床试验 |
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纯度： 98%
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