S186是新型锶特异性螯合剂。
| 生物活性 |
S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent. IC50 value: Target: In a case test for 4 person who took 90Sr in due to an internal contaminated accident, the APAP was adminstrated intramuscularly once a day for 3 days, the increase excretion of 90Sr was obvious and no side effects was observed among them. Recently, S186 has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China. |
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| 分子式 |
C5H13NO7P2.Ca+2.Na+
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| 分子量 |
321.15
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| CAS号 |
97759-16-5
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble) |
纯度： ≥95%
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