UK-240455
目录号 : KG12605
CAS No. : 178908-09-3
纯度 : 98%
UK-240455 is a potent and selective N-methyl D-aspartate (NMDA) glycine site antagonist.
UK-240455 is a potent and selective N-methyl D-aspartate (NMDA) glycine site antagonist. Following i.v. administration of UK-240455 to male rats, UK-240455 has a clearance of 12 mL/min/kg and a volume of distribution of 0.4 L/kg. The plasma concentration of UK-240455 decreases with an apparent half-life of 0.4 h. Analysis of urine (0 to 24 h) for unchanged UK-240455 indicates that 57% of the dose administered is excreted unchanged in the urine. The urinary clearance of UK-240455 in the rat is therefore 7 mL/min/kg. Following oral administration of UK-240455 to male rats, the apparent elimination half-life of UK-240455 from plasma following oral administration is 1.6 h.
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| 分子式 |
C11H11Cl2N3O5S
|
| 分子量 |
368.19
|
| CAS号 |
178908-09-3
|
| 中文名称 |
UK-240455
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|