COX2-IN-1 - CAS:134729-13-8

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COX2-IN-1 (Synonyms:1-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]-pyrazole-3-carbonitrile)

目录号 : KG12379 CAS No. : 134729-13-8 纯度 : 98%

Data Sheet 产品使用指南

COX2-IN-1 is a selective and inducible COX2 inhibitor with an IC50 of 0.24 μM. COX2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities. COX2-IN-1 shows no COX-1 inhibition even at 100μM. COX2-IN-1 has oral ED50 values of 0.030 and 0.47mg/kg on adjuvant-induced arthritis and collagen-induced arthritis, respectively, and an ED30 value of 7.4mg/kg in the yeast-induced hyperalgesia (Randall-Selitto) assay. COX2-IN-1 shows good analgesic activity and no ulcerogenicity.

规格	价格	是否有货	数量
1mg		In-stock
5mg		In-stock
10mg		In-stock
20mg		In-stock

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分子式

C₁₇H₁₂FN₃O₂S

分子量

341.36

CAS号

134729-13-8

中文名称

1-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]-pyrazole-3-carbonitrile

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： 98%

Data Sheet

产品使用指南

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