Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations.
体外研究
Maytansine, at 6x10 M, irreversibly inhibits cell division in eggs of sea urchins and clams. Maytansine causes the disappearance of a mitotic apparatus or prevents one from forming if added at early stages. Maytansine inhibits in vitro polymerization of tubulin.
分子式
C34H46N3O10Cl
分子量
692.20
CAS号
35846-53-8
运输条件
Room temperature in continental US; may vary elsewhere.