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VU 0424465
目录号 : KG11992 CAS No. : 1428630-85-6 纯度 : 98%
Data Sheet 产品使用指南
Potent mGlu5 positive allosteric modulator (EC50 = 1.5 nM) and agonist (EC50 = 171 nM; maximum effect is 65% that of glutamate). Binds allosteric site with high affinity (Ki = 11.8 nM). Increases maximum response to glutamate by 30%. Exhibits bias towards signaling via IP1 and ERK1/2 over iCa2+ in HEK293 and neuronal cells, and activates Gs in HEK 293 cells. Induces epileptiform activity in CA3 hippocampal neurons in vitro and convulsions in vivo.
规格 价格 是否有货 数量
10mg
In-stock
50mg
In-stock
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Other Forms of Rapamycin:

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分子式
C19H19FN2O2
分子量
326.37
CAS号
1428630-85-6
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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