Timepidium bromide (Sesden)
(Synonyms:噻哌溴铵;3-(二噻吩-2-基亚甲基)-5-甲氧基-1,1-二甲基-1-哌啶鎓溴化物)
目录号 : KG11968
CAS No. : 35035-05-3
纯度 : 98%
Timepidium bromide (Sesden; SA504) is an anticholinergic agent.
Effects of Timepidium bromide (TB), acetylcholine (ACh) and neostigmine (Neost) on gastric and duodenal blood flow distribution are studied by the use of 131I-labeled macroaggregated human serum albumin (MAA) in rabbits. In normal rabbits, gastric blood flow is found to be uneven in various regions of the stomach: anterior corpus (50% of total gastric blood flow) greater than posterior corpus (40%) greater than pyloric antrum (7%). Intravenous administration of Timepidium bromide (200 μg/kg) to normal rabbits produces a slight increase in total gastric blood flow, but the increase in the mucosal layer of the pyloric antrum is considerable.
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| 分子式 |
C17H22BrNOs2
|
| 分子量 |
400.4
|
| CAS号 |
35035-05-3
|
| 中文名称 |
噻哌溴铵
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|