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Tertatolol ((±)-Tertatolol) (Synonyms:1-(叔-丁基氨基)-3-[(3,4-二氢-2H-1-苯并噻喃-8-基)氧基]丙-2-醇)
目录号 : KG11965 CAS No. : 83688-84-0 纯度 : 98%
Data Sheet 产品使用指南
Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects. In serum-free media, tertatolol does not significantly alter the incorporation of 3H-thymidine after 28 h of incubation in human mesangial cell (HMC). In the presence of 1% serum, tertatolol significantly reduces 3H-thymidine incorporation. Tertatolol also inhibits 3H incorporation when PDGF and thrombin are used as the stimulus. Tertatolol inhibits the reduction in planar surface area of HMC induced by angiotensin II. The inhibitory effect of tertatolol on HMC proliferation is also potentiated by ritanserin and MDL 72222, 5HT2 and 5HT3 antagonists, respectively.
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20mg
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分子式
C16H25NO2S
分子量
295.44
CAS号
83688-84-0
中文名称
1-(叔-丁基氨基)-3-[(3,4-二氢-2H-1-苯并噻喃-8-基)氧基]丙-2-醇
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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