β3-AR agonist 2
(Synonyms:L-Leucine, N-[4-[4-[[(2R)-2-hydroxy-2-[4-hydroxy-3-[(methylsulfonyl)amino]phenyl]ethyl]amino]-1-piperidinyl]benzoyl]-)
目录号 : KG11324
CAS No. : 340757-05-3
纯度 : 98%
β3-AR agonist 2 is a potent and selective β3-adrenergic receptor (β3-AR) agonist with an EC50 of 8 nM.
β3-AR agonist 2 (Compound 26e) is found to be potent and selective at the β3 receptor, nearly completely abolishes intrinsic activity at either the β1 or β2 receptor.
β3-AR agonist 2 (Compound 26e) has significant thermogenesis effects on human β3-adrenergic receptor transgenic mice. β3-AR agonist 2 acts as a potential drug for the treatment of human obesity and type II diabetes.
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| 分子式 |
C27H38N4O7S
|
| 分子量 |
562.68
|
| CAS号 |
340757-05-3
|
| 中文名称 |
L-Leucine, N-[4-[4-[[(2R)-2-hydroxy-2-[4-hydroxy-3-[(methylsulfonyl)amino]phenyl]ethyl]amino]-1-piperidinyl]benzoyl]-
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|