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VO-OHpic (Synonyms:VO-OHpic)
目录号 : KG10693 CAS No. : 675848-25-6 纯度 : 98%
Data Sheet 产品使用指南
Potent inhibitor of PTEN (phosphatase and tensin homolog) (IC50 = 35 nM). Displays selectivity for PTEN over cysteine-based phosphatases such as SopB, MTM, PTPβ and SAC (IC50 values are 588 nM, 4.03, 57.5 and >10 μM respectively). Increases PIP2 and PIP3 levels; also increases Akt translocation in NIH/3T3 fibroblasts. Blocks the immunosuppressant activity of IDO-activated Tregs. Promotes antitumor inflammatory response in combination with immunotherapy and enhances anticancer chemotherapy in tumor-bearing mice.
规格 价格 是否有货 数量
10mg
In-stock
50mg
In-stock
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分子式
C12H10N2O8V
分子量
361.16
CAS号
675848-25-6
中文名称
VO-OHpic
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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