TW9 - CAS:2614417-90-0 - KKL Med Inc.

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TW9

目录号 : KG10493 CAS No. : 2614417-90-0 纯度 : 98%

Data Sheet 产品使用指南

TW9 is a dual inhibitor of bromodomain 2 (BD2) in bromodomain-containing protein 4 (BRD4) and histone deacetylase 1 (HDAC1; IC50s = 0.074 and 0.29 µM, respectively). It is selective for BD2 over BD1 in BRD4 (IC50 = 0.72 µM) and for HDAC1 over HDAC2 (IC50 = 2.5 µM). TW9 (50 nM) induces apoptosis in, and inhibits proliferation of, MIA PaCa-2 pancreatic cancer cells. It induces cell cycle arrest at the G1 phase in HPAC pancreatic cancer cells when used at a concentration of 2 µM. TW9 acts synergistically with gemcitabine to reduce the viability of HPAC cells.

规格	价格	是否有货	数量
1mg		In-stock
5mg		In-stock

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分子式

C₃₂H₂₈ClN₇O₂S

分子量

610.1

CAS号

2614417-90-0

中文名称

NND-2242001

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： 98%

Data Sheet

产品使用指南

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