Tubulysin B
(Synonyms:Tubulysin B)
目录号 : KG10383
CAS No. : 205304-87-6
纯度 : 98%
Tubulysin B is a highly cytotoxic peptide and potent microtubule destabilizing agents isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin B has IC50 values in the picomolar range against many cancer cell lines, including those with multidrug resistant properties.Tubulysin B is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis.
Tubulysin B has IC50s of 0.6 and 0.9 nM against KB and A549 tumors cell lines, respectively.
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| 分子式 |
C42H63N5O10S
|
| 分子量 |
830.04
|
| CAS号 |
205304-87-6
|
| 中文名称 |
Tubulysin B
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|