Tubulysin A (TubA) (Synonyms:N-(2-氨基-2-氧代乙基)-N-(羧甲基)甘氨酸)
目录号 : KG10382 CAS No. : 205304-86-5 纯度 : 98%
Tubulysin A(TubA) is a myxobacterial product that can function as an antiangiogenic agent in many in vitro assays; anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative.IC50 value: Target: microtubuleTubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins are cytotoxic peptides, which include 9 members (A-I). Tubulysin A has potential application as an anticancer agent. It arrests cells in the G2/M phase. Tubulysin A inhibits polymerization more efficiently than vinblastine and induces depolymerization of isolated microtubules. Tubulysin A has potent cytostatic effects on various tumor cell lines with IC50 in the picomolar range.
规格 价格 是否有货 数量
1mg
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分子式
C43H65N5O10S
分子量
844.07
CAS号
205304-86-5
中文名称
N-(2-氨基-2-氧代乙基)-N-(羧甲基)甘氨酸
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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