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Dibenzylfluorescein
目录号 : KCM15961 CAS No. : 97744-44-0 纯度 : ≥98%
Data Sheet 产品使用指南
Dibenzylfluorescein is a fluorogenic probe that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is dealkylated by these CYP isoforms to produce fluorescein benzyl ether, which is further hydrolyzed to fluorescein by the addition of base (typically 2 M NaOH). Dibenzylfluorescein is typically used near its apparent K value of 0.87-1.9 µM. The fluorescence of fluorescein is evaluated using excitation/emission wavelengths of 485/538 nm. Dibenzylfluorescein is used to detect changes in CYP catalytic activity caused by drugs or disease.
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1mg
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5mg
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10mg
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25mg
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分子式
C34H24O5
分子量
512.6
CAS号
97744-44-0
中文名称
Benzyl 2-[6-(benzyloxy)-3-oxo-3H-xanthen-9-yl]benzoate
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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