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Diclofenac Acyl-β-D-Glucuronide (Synonyms:双氯芬酸酰基-β-D-葡糖苷酸;6-[2-[2-(2,6-二氯苯胺基)苯基]乙酰基]氧基-3,4,5-三羟基-四氢吡喃-2-羧酸)
目录号 : KCM14672 CAS No. : 64118-81-6 纯度 : ≥95%
Data Sheet SDS 产品使用指南
Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat. Diclofenac acyl-β-D-glucuronide is acutely toxic in vitro, suggesting it may play a role in the hepatotoxicty of diclofenac in vivo. Diclofenac acyl-β-D-glucuronide binds to organic anion transporters (OATs; K = 60.2, 8.6, 112, and 103.9 µM for OAT1-4, respectively) as well as multi-drug resistance proteins. High levels of diclofenac are found in waste water treatment plant samples, which may be due to the back-transformation of diclofenac acyl-β-D-glucuronide to diclofenac.
规格 价格 是否有货 数量
500μg
In-stock
1mg
In-stock
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分子式
C20H19Cl2NO8
分子量
472.3
CAS号
64118-81-6
中文名称
6-[2-[2-(2,6-二氯苯胺基)苯基]乙酰基]氧基-3,4,5-三羟基-四氢吡喃-2-羧酸
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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