Ellipticine
(Synonyms:椭圆玫瑰树碱;玫瑰树碱;椭圆玫瑰树碱溶液;5,11-二甲基-6H-吡啶并[4,3-B]咔唑;5,11-二甲基吡啶并[4,3-b]咔唑;Ellipticine 抑制剂;玫瑰树碱(RG))
目录号 : KCM14074
CAS No. : 519-23-3
纯度 : ≥95%
Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/5 Inhibitor is a pyrazolo [3,4-b] quioxaline that inhibits Cdk1/cyclin B and Cdk5/p25 (ICs = 600 and 400 nM, respectively). It less potently inhibits GSK3β (IC = 1 µM) and does not block Cdc25 activity. This compound is used to help define the roles of Cdk1 and Cdk5 in various signaling pathways.
Other Forms of Rapamycin:
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| 分子式 |
C9H7N5
|
| 分子量 |
185.2
|
| CAS号 |
519-23-3
|
| 中文名称 |
椭圆玫瑰树碱
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|