EM574
(Synonyms:伊屈西那)
目录号 : KCM10326
CAS No. : 110480-13-2
纯度 : ≥98%
EM574 is a motilin receptor agonist with an IC value of 6.17 nM for binding to rabbit gastric antral smooth muscle homogenates in a radioligand binding assay. It also binds to human smooth muscle homogenates in a radioligand binding assay (K = 7.8 nM). EM574 induces contraction of isolated rabbit, but not rat or guinea pig, intestine (EC = 5.5 nM). It increases antral motility and enhances gastric emptying in canine models of gastroparesis when administered intraduodenally at a dose of 0.03 mg/kg following a semi-solid meal.
Other Forms of Rapamycin:
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| 分子式 |
C39H69NO12
|
| 分子量 |
743.9647
|
| CAS号 |
110480-13-2
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|