L-Glutamic acid 作为一种兴奋性氨基酸神经递质，为谷氨酸盐受体所有亚型(代谢型红藻氨酸、NMDA 和 AMPA)的激动剂。对 DA 从多巴胺能神经末梢释放的过程有激动作用。
| 生物活性 |
L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals. |
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| 体外研究 |
L-Glutamic acid could act on [H]DA release through presynaptic glutamatergic receptors. L-glutamic acid (50 μM) still stimulated the release of [H] DA in the presence of tetrodotoxin (0.5 μM). |
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| 分子式 |
C5H9NO4
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| 分子量 |
147.13
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| CAS号 |
56-86-0
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| 中文名称 |
L-谷氨酸
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
H2O : 6.25 mg/mL (42.48 mM; Need ultrasonic) DMSO : 2 mg/mL (13.59 mM; ultrasonic and warming and heat to 60°C) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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| 临床试验 |
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纯度： ≥98%
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Data Sheet