Microcystin LA, a natural toxin, exerts its cytotoxic exects by inhibiting the serine-threonine protein phosphatases PP1 and PP2A with IC50s of 0.3 and 0.3 nM, respectively.
体外研究
Microcystin LA inhibit PP1 and PP2A quite potently and specifically relative to other known phosphatases, such as PP2B (calcineurin), PP2C, and the tyrosine phosphatases.
分子式
C46H67N7O12
分子量
910.06
CAS号
96180-79-9
中文名称
微囊藻毒素-LA
运输条件
Room temperature in continental US; may vary elsewhere.