Zonisamide-d4 (AD 810-d4) 是 Zonisamide 的氘代物。Zonisamide (AD 810) 是锌酶碳酸酐酶 (carbonic anhydrase) 的抑制剂，对人类线粒体同工酶 hCA II 和 hCA V 作用的 Ki 值分别为 35.2 nM 和 20.6 nM。Zonisamide 具有抗癫痫活性。Zonisamide 可用于癫痫、癫痫发作和帕金森病的研究。
| 生物活性 |
Zonisamide-d4 (AD 810-d4) is the deuterium labeled Zonisamide. Zonisamide (AD 810) is an inhibitor of zinc enzyme carbonic anhydrase (CA), with Kis of 35.2 nM and 20.6 nM for human mitochondrial isozyme hCA II and hCA V, respectively. Zonisamide has antiepileptic activity. Zonisamide can be used for the rsearch for epilepsy, seizures and Parkinson's disease. |
|---|---|
| 体外研究 |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. |
| 分子式 |
C8H8N2O3S
|
| 分子量 |
216.25
|
| CAS号 |
1020720-04-0
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
客服小K 
客服小K
Data Sheet
