PTP1B-IN-4 是一个非竞争性的蛋白质酪氨酸磷酸酶 PTP1B 变构抑制剂，其 IC50 值为 8 μM。PTP1B-IN-4 有望用于肥胖症和糖尿病的研究。
| 生物活性 |
PTP1B-IN-4 is a non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B, with an IC50 of 8 μM. PTP1B-IN-4 is potentail for the research of obesity and diabetes. |
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| 体外研究 |
PTP1B-IN-4 (250 µM; 1 hour) stimulates insulin receptor (IR) phosphorylation in CHO cells overexpressing human IR. Western Blot Analysis
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| 分子式 |
C26H19N3O7S3Br2
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| 分子量 |
741.45
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| CAS号 |
765317-72-4
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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