Dehydrocorydaline nitrate (13-Methylpalmatine nitrate) 是一种生物碱。Dehydrocorydaline 调节 Bax，Bcl-2 蛋白表达；激活 caspase-7，caspase-8，并使 PARP 失活。Dehydrocorydaline nitrate 能增强 p38 MAPK 活化，具有抗炎、抗癌等功效。。Dehydrocorydaline nitrate 具有强大的抗疟疾作用，并具低细胞毒性 (细胞生存力> 90％)， P. falciparum 3D7 strain (IC50=38 nM)。
| 生物活性 |
Dehydrocorydaline nitrate (13-Methylpalmatine nitrate) is an alkaloid. Dehydrocorydaline regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline nitrate elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities.. Dehydrocorydaline nitrate shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain. |
|---|---|
| 分子式 |
C22H24NO4+.NO3-
|
| 分子量 |
428.44
|
| CAS号 |
13005-09-9
|
| 中文名称 |
硝酸脱氢紫堇碱；硝酸去氢紫堇碱；硝酸脱氢紫堇硷；硝酸脱氢延胡索碱；硝酸去氢延胡索碱
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 科研文献 |
|
纯度： 98%
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