NFAT Inhibitor - CAS:249537-73-3

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NFAT Inhibitor (Synonyms:VIVIT peptide)

目录号 : KM17584 CAS No. : 249537-73-3 纯度 : 98%

Data Sheet 产品使用指南

NFAT Inhibitor (VIVIT peptide) 是一种 NFAT 的细胞渗透性肽抑制剂，可选择性抑制钙调磷酸酶介导的 NFAT 脱磷酸作用。

规格	价格	是否有货
1mg		In-stock
5mg		In-stock
10mg		In-stock
25mg		In-stock
50mg	询价	In-stock
100mg	询价	In-stock

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生物活性

NFAT Inhibitor (VIVIT peptide) is a cell-permeable peptide inhibitor of nuclear factor of activated Tcells (NFAT) that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.

体外研究

NFAT Inhibitor treatment significantly inhibits nuclear translocation of NFATc1 for 24 hours. Long-term treatment with VIVIT significantly inhibits the cytoplasmic levels of cathepsin K, TRAP, and MMP-9.

Western Blot Analysis

Cell Line:	Human peripheral blood CD14 monocytes
Concentration:	10 μM
Incubation Time:	24 hours or 21 days
Result:	Short-term treatment with 10 μM, significantly inhibited nuclear translocation of NFATc1. Long-term treatment, significantly inhibited the cytoplasmic levels of cathepsin K, TRAP, and MMP-9.

分子式

C₇₅H₁₁₈N₂₀O₂₂S

分子量

1685.94

CAS号

249537-73-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-80°C	2 years
	-20°C	1 year
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

H₂O : 100 mg/mL (59.31 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.5931 mL	2.9657 mL	5.9314 mL
5 mM	0.1186 mL	0.5931 mL	1.1863 mL
10 mM	0.0593 mL	0.2966 mL	0.5931 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

科研文献

纯度： 98%

Data Sheet

产品使用指南

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Other Forms of Rapamycin:

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