Pinocembrin (5, 10, 25, 50, 100 or 200 µM, 24 hours) significantly reduces cell viability of RBL-2H3 cells.
Pinocembrin (25 or 50 µM) suppresses iNOS, PGE-2 and COX-2 levels, increases p38-Mapk and IкB-α, and inhibits phosphorylation of IкB-α.
Cell Viability Assay
Cell Line: |
RBL-2H3 cells |
Concentration: |
5, 10, 25, 50, 100 or 200 µM |
Incubation Time: |
24 hours |
Result: |
Decreased cell viability by ∼50% at ≥ 100 µM. Showed 75% cell viability at lower concentrations. |