Insulin cattle (Insulin from bovine pancreas) is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells.
体外研究
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates glucose uptake into muscle and fat cells by recruiting membrane glucose transporter Glut-4 to cell surface. Insulin cattle has often been used as growth supplement in culturing cells at the concentration ranging from 1 to 10 μg/mL of medium.
分子式
C254H377N65O
分子量
5733.49
CAS号
11070-73-8
中文名称
牛胰岛素
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder
-80°C
2 years
-20°C
1 year
In solvent
-80°C
6 months
-20°C
1 month
溶解性数据
In Vitro:
H2O : 11 mg/mL (1.92 mM; ultrasonic and adjust pH to 2 with HCl)