Fmoc-NH-PEG2-CH2CH2COOH
目录号 : KM13039 CAS No. : 872679-70-4 纯度 : 98%

Fmoc-NH-PEG2-CH2CH2COOH 是一种可降解的 ADC linker,用于抗体药物偶联物 (ADC) 合成。Fmoc-NH-PEG2-CH2CH2COOH 也是一种基于 PEG 的 PROTAC linker,可用于 PROTAC 的合成。

规格 价格 是否有货 数量
100mg
In-stock
200mg 询价 In-stock
500mg 询价 In-stock

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生物活性

Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG2-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

体外研究

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

分子式
C22H25NO6
分子量
399.44
CAS号
872679-70-4
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
暂无相关参考文献
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