Becampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent.
体外研究
Becampanel is negative in a mouse lymphoma tk assay, which includes a 24 h treatment without S9. A weak micronucleus induction in vitro is found at the highest concentrations tested in V79 cells with S9.
体内研究
Becampanel is negative in the following in vivo studies, which includes the maximum tolerated doses of 320 mg/kg in mice and 2000 mg/kg in rats. Becampanel has no genotoxic potential in vivo.
分子式
C10H11N4O7P
分子量
330.19
CAS号
188696-80-2
运输条件
Room temperature in continental US; may vary elsewhere.