| 生物活性 |
Tz-Thalidomide is a tetrazine tagged Thalidomide (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2). Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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| 分子式 |
C29H29N7O6
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| 分子量 |
571.58
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| CAS号 |
2087490-42-2
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| 中文名称 |
6-((2-(2,6-二氧代哌啶-3-基)-1,3-二氧代异吲哚啉-4-基)氧基)-N-(4-(6-甲基-1,2,4,5-四嗪-3-基)苄基)己酰胺
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
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纯度： 98%
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