| 生物活性 |
Tyk2-IN-22-d3 (Compound 1) is the deuterated analog of Tyk2-IN-22 . Tyk2-IN-22 (Compound A8) is a selective inhibitor for tyrosine kinase 2 (Tyk2), that it inhibits Tyk2, JAK1, and JAK3 with IC50s of 9.7, 148.6, and 883.3 nM, respectively. Tyk2-IN-22 inhibits the downstream STAT5 phosphorylation.
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| 分子式 |
C20H19D3N8O3
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| 分子量 |
425.46
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| CAS号 |
1771691-32-7
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
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