Vortioxetine-d3
目录号 : KM35200 CAS No. : 1629684-22-5
Vortioxetine-d3 (Lu AA 21004-d3) 是氘代标记的 Vortioxetine 。Vortioxetine (Lu AA 21004) 是 5-HT3A,5-HT7 受体的拮抗剂 (Ki: 3.7 nM,19 nM) 和 5-羟色胺转运体 (SERT) 的抑制剂 (Ki: 1.6 nM),还是 5-HT1A 的激动剂和 5-HT1B 的部分激动剂 (Ki: 15 nM,33 nM)。
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生物活性
Vortioxetine-d3 (Lu AA 21004-d3) is a deuterium labeled Vortioxetine . Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of serotonin transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial agonist of 5-HT1B (Ki: 15 nM, 33 nM).
分子式
C18H19D3N2S
分子量
301.46
CAS号
1629684-22-5
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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