2,5-Deoxyfructosazine-13C4 (Synonyms:2,5-Deoxyfructosazine-13C4)
目录号 : KM34402 CAS No. : 1246815-27-9
2,5-Deoxyfructosazine-13C4 (NSC 270912-13C4) 是 13C 标记的 2,5-Deoxyfructosazine 。2,5-Deoxyfructosazine (NSC 270912) 是一种吡嗪衍生物,存在于烤烟中,在食品和烟草工业中用作调味剂。吡嗪(包括 2,5-Deoxyfructosazine (NSC 270912))可通过天然化合物的热解分解或糖与醇氨的反应产生。2,5-Deoxyfructosazine (NSC 270912)也可由中性 pH 下的 D-葡萄糖胺分解形成。与葡萄糖胺一样,2,5-Deoxyfructosazine (NSC 270912) 具有 DNA 链断裂活性,并强烈抑制植物血凝素刺激的 Jurkat 细胞产生 IL-2(IC50=~1.25 mM)。
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生物活性
2,5-Deoxyfructosazine-13C4 (NSC 270912-13C4) is the 13C-labeled 2,5-Deoxyfructosazine . 2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM).
分子式
C813C4H20N2O7
分子量
308.27
CAS号
1246815-27-9
中文名称
2,5-Deoxyfructosazine-13C4
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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