Resolvin D2 (Synonyms:RvD2)
目录号 : KM10892 CAS No. : 810668-37-2

Resolvin D2 是 DHA 的代谢物,具有抗炎和抗感染活性。Resolvin D2 是一种高效的白细胞调节器,能控制微生物败血症。在原代感觉神经元中,Resolvin D2 是 TRPV1 (IC50 = 0.1 nM) 和 TRPA1 (IC50 = 2 nM) 的有效抑制剂。

规格 价格 是否有货 数量
25μg
In-stock
50μg
In-stock

Other Forms of Rapamycin:

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生物活性

Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons.

体内研究

Resolvin D2 induces active resolution of inflammation with pulp-like tissue regeneration after root canal infection and thus maybe suitable for treating periapical lesions.
Resolvin D2 decreases leukocyte:endothelial interactions in vivo by endothelial-dependent nitric oxide production, and direct modulation of leukocyte adhesion receptor expression.
Peripheral administration of Resolvin D2 (10 ng; Intraplantar administration) potently inhibits inflammatory pain.

Animal Model: Adult CD1 mice (male, 8–10 weeks)
Dosage: 10 ng
Administration: Intraplantar administration
Result: Inhibited inflammatory pain.
分子式
C22H32O5
分子量
376.49
CAS号
810668-37-2
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Solution, -20°C, 2 years

科研文献
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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