致电 400-881-9290
登录/ 注册
0 我的购物车
您当前的位置：
  1. 首页
  2. Signal path
  3. Cell Cycle/DNA Damage | 细胞周期/DNA 损伤
  4. DNA Alkylator/Crosslinker
PIP-199
目录号 : KM10867 CAS No. : 622795-76-0 纯度 : 98%
Data Sheet 产品使用指南

PIP-199 是一种 RecQ 介导的基因组不稳定蛋白 RMI 核心复合物/MM2 相互作用 (RMI core complex/MM2 interaction) 的选择性抑制剂，其 IC50 值为 36 μM。PIP-199 可用于耐受肿瘤对 DNA 交联化疗药物的增敏研究。

规格 价格 是否有货 数量
5mg
In-stock
10mg
In-stock
加入购物车 大包装询价

Other Forms of Rapamycin:

KKL Med 的所有产品和服务仅用于科学研究，不能被用于人体，兽医，我们也不向个人提供产品和服务。
生物活性

PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics.

体外研究

MM2 is the binding site of RMI complex on Fanconi anemia complementation group M protein (FANCM).
Induction of the Fanconi anemia (FA) DNA repair pathway is a common mechanism by which tumors evolve resistance to DNA crosslinking chemotherapies.
Proper execution of the FA pathway requires interaction between the FANCM and the RMI complex, and mutations that disrupt FANCM/RMI interactions sensitize cells to DNA crosslinking agents.
分子式
C27H28N4O3
分子量
456.54
CAS号
622795-76-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
暂无相关参考文献
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
重置 计算
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
重置 计算
联系我们
400-881-9290

technical-service@kklmed.com

terminal-order@kklmed.com

terminal-inspection@kklmed.com

dealer-order@kklmed.com

 10338 stony run ln，ste121，ashland，va，23005，USA
KKL MED 小分子
KKL MED

关注我们

获得KKL MED 最新资讯

Copyright © 2013-2022 KKL Med Inc. All Rights Reserved. 粤ICP备2022038512号-1
首页 分类 购物车 会员